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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5affe8540fc066ce2e0b67194d1d794c93e1d06155e75dfc95bd237c8c84cc6e' 
  AND token = '16WIULofn/FO1A0EjWyDAZU+e2xTdXAcuhQxKPT1jkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}