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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a79886fb39ee8c1af60adc0f7e64e11675df9a4794dca8921da7e59d900d19e5' 
  AND token = 'id45qs6A3ARZ19CT8SnC03GDM+HEnsAnqsow0VcoUYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}