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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfd9ee244860e8a87ac674b3e99e35d80b71a385fb827e31180deec7eccf5f34' 
  AND token = 'naW6S4GSeeULYYkd2zFzHcjroT06AgiP9o50O+Itpfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}