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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa99dd0d4b6d0acad217017dc5da55332b86f461bbbaea3ae44806b3eca35334' 
  AND token = 'UNeORX2MI4xjmeIJET9HLLvWbBRvwJjKyi4WVkEL7Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}