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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f9ce46586112464a55de65654b9fad5888d8efd8d82cf8b9234aca5a47385bdc' 
  AND token = 'D3jSO2QLW0pDEpt8GfpCnBTvZtnIz53MIC9EZA3R2Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}