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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '81f4e5ac9f64715a80d8914144e840689f93783006ed1a3c5c445f65b3fcb393' 
  AND token = 'p168HX1EbsxZ7pMhdxN0EFbDNUWFHctK9u3u8czU8Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}