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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd7545dc9c26f44c016c471a3aab478cb64724076715f8bab12e0e52b36114afd' 
  AND token = 'IZ36rXpsod0PUSWcha4XQGWr+td10Lq97WJrrkMi8RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}