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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '381288fad8c1d4c4efa9cb8f47b2481b62bc55cec9aa2941647c13b6d357abcd' 
  AND token = 'TKLUQUfA+QbtHyuNrSl37QMHX8BX0O0B7EmCL/aaaZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}