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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc026eddd89df931fe441bc05e69f8e4650265a96d7671c69a2a10069a030859' 
  AND token = '+f81KiT1LB50tXBNELiN/RaNwmiqDcrXfvhqLhtmtjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}