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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f2ddcf88fd01733b57e7652727e423bda1779ba3dc9feaceeb7b5c35363e7d50' 
  AND token = 'iw9rW2RY0273bH/UgNzUAcoMY1gBlyRc//PMjaY5Xwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}