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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b446a4db2ca21551612cf9303e56034cebb3bf45d9c2a330d005bd8e3ee97fca' 
  AND token = '/IO2AwaLEAgbqDKZcuL1NYkx0KynJsZpQTbLsnS/Pms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}