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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61d0357d0adb566097910fed764fd1207f33d067bb2cfa2a49a15e443710f4b7' 
  AND token = 'GZV37/JsvdSfNC+SToX5NQNh0cwvN9U3lcFlvqaL/c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}