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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50278183c4a6b8f1b625c1cc7d68d74359144bc889dc96071804d093e2a25a0b' 
  AND token = 'bulYpMS1pqpoClrqaUdUN3AVEd84FQ95yozdOSsoH5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}