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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c01000bdf4b21a65d3ef1bb2c73bada365275363d4008e9f966ffffc3577716' 
  AND token = 'eXWX5JNB/Zu0RmoDMPsFCbkA0DnCCvEi7NKyTMpqwnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}