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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f9e54d1c62c03a1fad002e41544de84de7386a518646933b76c101a897f68a88' 
  AND token = 'RBlWfLPpoc2/LKLflVSTAuCbwNOtDQ66jfr/tl63gfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}