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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e434fdc21a4f451a59199c39b0b65559716af809e6f76565f39635b176fab065' 
  AND token = 'Mh3Ldd8ydLc9t7gR7AZqBQhg5umz5X9TC8av16BxoqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}