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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '40c22ab18a4e6bf1469afaa7aac951ae0cd40fa379b3f74beb6003fa6d74ff46' 
  AND token = 'lK+cepFIVzm3fi2/RZ+5n33zIxe3HMJhY0t44eC8hkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}