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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf64e5d3aeba557bcfb57cc041af90f363e4d84330cae13260ff12ee87c15791' 
  AND token = 'fqA3U48mWf7ZkbVjfqDjffsuzNhsB6dW9znIEc65wmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}