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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f65226f10543bcdfa78a26a2aead49bb4ea2d426677fc6863f705e2ec2c22364' 
  AND token = '0JFGf4DCErRqrDYTKUMdoUAeQe4od2PWragzlQdHsVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}