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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '416ec8e4acc3cc8e164ea917a98f3489bc261c2c5b7bf5407c22dc0f70221c65' 
  AND token = 'RY54FA8YE2YO/p3W+WrcU8vwt1SVc72rHFJXAzPcqD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}