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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53925cf2945ef3b273ae0f17e20fa035d571b7c00450d97c4264eac12bbebaab' 
  AND token = 'nQ+d4Wp9xiHXxAFtqJ8G+74YXbJbcx0+dHooV5zIaV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}