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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22ac575e6431c4a89e91dc5795250f11aa0a664e5d66f6eb7950d52b16abc502' 
  AND token = 'qPCXIb20+DiJKQUhLsGx7oQY+YhiFrp0HUA850aoGgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}