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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3d0a04bd1613823f70dc6bd9596091d56d2d7675b260720333ede5715c0d5d1' 
  AND token = 'GJm6MtOM0QtUGljEoWwsp1JtSg9fRMyZl7OhMjetsBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}