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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '18a8e1f63f47b45f80651bf8295e2a0734eae7cf01ba10ccc08bd0cfde8fefe9' 
  AND token = '9qP3jcEJHZ4z/jc+v2ivk7bNHkKErsWvlZHcJmUNh3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}