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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1d90db5e4ec7521a4424335f0221c2de85b4595fc5dc88b85da342b8556468f6' 
  AND token = 'epOCiXpen/csqqRFPJgdOPeCXcg7LBHtzYGsJcSaeko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}