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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b34285012f38acc2b15a710e8b8043c80b4c52edda5aeccf3a2cca8cee72a22' 
  AND token = 'C22cDOXIS2+lW4aQrelTCfQGK95ShLSN4m+w6My0b+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}