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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '52929727d7bf93bfe58eeef267354113b0b4cb45c35de7bc1563391c4c83d8d6' 
  AND token = 'B77UCmSzwQdN0diMaUrb/3WNznvWBdydjzGr4RAz05Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}