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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '253572ff72d8138cb4ab7d400b2c32e1df40cd1dc6dbe7253e2d067c32b78531' 
  AND token = 'Xmqw1Tq5RCuHTGS/rCRuLOpziC7vfaCmAX1YbxS7qs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}