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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '431fdf3aae13778165b8f6a5ebea7f5983c12051a81201968839a56bf5047741' 
  AND token = 'GsoRvIimyCUVtQOO/J8j+6HRF6xUtHHdI2tiIpQ1NTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}