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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e645dfdd1522c3728f460e29a01b36815d0f53adcad40ee660903b63e2d0d176' 
  AND token = 'UCEHk3xQbNXYaoy/EvPmcl/aLfjS8SRfLbFcGPfbmCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}