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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2157dc48c7a3f4ca59340083f5cf3f6829ddb95e3b8569dee6a815e31b85b0b7' 
  AND token = 'bvzjtOhx6WIg8UbSPHLCNrF/Ju6R/C3PTL0AI69oi7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}