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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3736426fbfa57744bb23cc580af9859bf34e0c20a38f9836138924dca6835a41' 
  AND token = 'z9NSgaZgz2c7aaucYv+PR4YcQiff7AVnRWORHm0ZEVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}