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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22e5654c947a094787526027a7cbf2f1ebe8c24d355ee66dfeae00d4434cc522' 
  AND token = 'ZxDKrOztjA94Mv2zR/20D5ovLqN9BlwdX4kAYV/f15o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}