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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00d5b8cbc09a025b4701d6069ad8c31cb9bb46add2ee69001f1f2bd0e7080938' 
  AND token = 'yFaI78+HWkWEStrwhJX3cNc+RBEZYaFZ2qMCF4A/ayo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}