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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9e5038971d336a264a3ef4143496018bac78e58428dce74c77ecffcd854f4b0b' 
  AND token = '+TIaKRrugOigj7uaDTKp1sgLz2vfwT0aQQDB8WS0Qi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}