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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2e7682dcdfa9dee1d3d94adf080dbc0342b271c4ec453b94369e845eef8c973' 
  AND token = 'CVDOzp5aoRyo9lrZO7rY0YNRLBi/oJi8W/+2E9l3Hx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}