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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0fa0d5dfa8bc337f52c4eec4f3249944189153abf77e765bebfe99abd23b18f3' 
  AND token = 'JXTP9AXdq6RhZexF0stC9UiFa67vpq6oIIr6CazkiIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}