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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f2e2e560bb66c9513aad495e1a356c21238759927e77e0df71a04ddecd7db9b' 
  AND token = '0czxNe8Q+oGqAlALFWVFTCDOBaldWQ5Ke3HTKUQ9gmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}