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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a99a13cf5ade45152a1ecf709ce7f7cf2ed378fa66f4586857cceb398beb521' 
  AND token = 'IguOSyX55N6T2AOsm3wmvsOqFtrYotVPDxasbuQMhPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}