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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f0f519925b3c3f8570daeda5e05826a8ee6508d1e8e52757dfb32e445cd13e8c' 
  AND token = 'fTumRqIJbUe2Vr3s926CGRhN83Y5HxsuIYfqzRioTv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}