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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '289190d24941eecd00fb2161356f45a0184c75cda3cd67228e764a849ca01600' 
  AND token = 'TtGGk5AXT/WPU2eSI7c2DpirHMuDBltRKZK4//a/jq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}