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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d1f78ebfb56d47d52401354434412324073492be2935cdbd8f84c8807030ae3' 
  AND token = '6u1L7BP0DTb9Qcr09QXAiT0rQW+hkgO6+z5aDR6zNbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}