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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dc0e84a64a68265a0fd3e6bef68e393ec0c5f103072e5a2be4a6705814ede0cf' 
  AND token = 'VMhzRnaOsAquDe3PZF1enT84bYDr/WDGXXfMvunKQVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}