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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'acfb580450c20edd476268b6cfcd9b2e77c0f10293bb6a7e9cedbd249bdbb946' 
  AND token = 'O5+QwLQRP2Rf+5T08HUoIwoU9fLHKpQ+YPL1jAZQE34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}