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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a43e1abb50ac157615df376fb35854fd19d0e800230fcffa74ce3ad647bc266c' 
  AND token = 'N3bo1kticoau7GEmYnokmpwlE2GCg0aMjMfIZYHcANY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}