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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '95d6e7bb7cc3282dbf23326a13c8d1cde8fce4548b82142b5eb678bc1be3e70f' 
  AND token = 'cF3LEXGb4ySHhqMDxxGDThTB8nkcKgK/L8EYZX4pp+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}