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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '90279b401d19fc274720d062016da57254e85c6fc24b964b966c34ab63495401' 
  AND token = 'cTA8xDNO0ZMw5gYAiklinyGRfOcCpxvRi2Sc3gNxVKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}