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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42a3bc449506fafafdd62e34c74e1fb603190b544be3f2768bf6527ed1c1ac43' 
  AND token = 'Kb2MfIGz0ejOIv1idvdVAHmndeQhaRrbB3AIw4DKT4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}