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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '405fadf4a5910df016d4fc72342722c0841ae2db3569d3d863fb1c7f7d825004' 
  AND token = '8t3YIN3gyKX2zOG7pqSZAIySP2ptbz5nt3COA3EOprM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}