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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43e20a4a7a080f199b39217f15696934594c0191f6c04301e3ee0bb4da6d5499' 
  AND token = 'ItejKYt69Y8Joio0d7jct0D7nSbgUKG23mm34fjsD1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}